Each 1 gm contains: Neomycin (As Neomycin sulphate) 200 mg. The active ingredient of NEOMIN PLUS 20% is neomycin which is a broad spectrum antibiotic. It is effective against a wide range of gram-negative and gram-positive bacteria including E.coli, Klebsiella, Haemophilus, Pseudomonas, Proteus, Salmonella, Shigella, Staphylococci and other organisms resistant to other antibiotics such as streptomycin. Neomycin is poorly absorbed from the gastrointestinal tract, therefore, provides antibiotic activity at the infection site and has no toxic effect if given orally